Pathogen Discovery and Characterisation (Proteomics)

PathogenThe overall aim is to provide genomics, proteomics and bioinformatics research and support to enable the PHE to rapidly assess the pandemic potential and evaluate the disease burden and risk posed from new and emerging infections. We intend to develop processes that will allow analysis of pathogens from small quantities of clinical material without the need for culturing or extensive clean-up. This will enable rapid identification of pathogens and the development of potential bio-markers for diagnostics, real-time monitoring of outbreaks and predictive modelling. In turn this will enable the formulation of policy that is better informed and can be developed more speedily in response to disease outbreaks.

 

More specific aims are:

  1. To establish an interdisciplinary, multi-institutional critical mass of researchers at the UoL and the PHE working together to exploit the latest omic technology for biomarker discovery, pathogen identification and surveillance and to investigate host-pathogen interactions
  2. Establish procedures and systems that allow this group of researchers to provide the necessary infrastructure in real-time during outbreaks to support public health responses
  3. Establish a world centre of excellence in the genomic, transcriptomic, and proteomic analysis of tissues from individuals infected with emerging infectious diseases

 

Theme Leaders

Miles CarrolProfessor Miles Carroll

Deputy Director, Head of Research

Public Health England

 

Roger HewsonProfessor Roger Hewson

Public Health England

 

 

 

 

 

Julian HiscoxProfessor Julian Hiscox

Professor of Infection and Global Health

Institute of Infection and Global Health, University of Liverpool